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1. Introduction.

Section I. MEASUREMENT BASICS.

2. Electrical Components and Circuits.
3. Operational Amplifiers in Chemical Instrumentation.
4. Digital Electronics and Microcomputers.
5. Signals and Noise.
Instrumental Analysis in Action: The Electronic Analytical Library.

Section II. ATOMIC SPECTROSCOPY.

6. An Introduction to Spectrometric Methods.
7. Components of Optical Instruments.
8. An Introduction to Optical Atomic Spectrometry.
9. Atomic Absorption and Atomic Fluorescence Spectrometry.
10. Atomic Emission Spectrometry.
11. Atomic Mass Spectrometry.
12. Atomic X-Ray Spectrometry.
Instrumental Analysis in Action: Monitoring Mercury.

Section III. MOLECULAR SPECTROSCOPY.
13. An Introduction to Ultraviolet/Visible Molecular Absorption Spectrometry.
14. Applications of Ultraviolet/Visible Molecular Absorption Spectrometry.
15. Molecular Luminescence Spectrometry.
16. An Introduction to Infrared Spectrometry.
17. Applications of Infrared Spectrometry.
18. Raman Spectroscopy.
19. Nuclear Magnetic Resonance Spectroscopy.
20. Molecular Mass Spectrometry.
21. Surface Characterization by Spectroscopy and Microscopy.
Instrumental Analysis in Action: Assessing the Authenticity of the Vinland Map.

Section IV. ELECTROANALYTICAL CHEMISTRY.
22. Introduction to Electroanalytical Chemistry.
23. Potentiometry.
24. Coulometry.
25. Voltammetry.
Instrumental Analysis in Action: Measuring the Parts to Understand the Whole.

Section V. SEPARATION METHODS.
26. An Introduction to Chromatographic Separations.
27. Gas Chromatography.
28. High-Performance Liquid Chromatography.
29. Supercritical Fluid Chromatography and Extraction.
30. Capillary Electrophoresis and Capillary Electrochromatography.
Instrumental Analysis in Action: Discovering Acrylamide.

Section VI. MISCELLANEOUS METHODS.
31. Thermal Methods.
32. Radiochemical Methods.
33. Automated Methods of Analysis.
34. Particle Size Analysis.
Instrumental Analysis in Action: The John Vollman Case.

Appendices.
Appendix 1. Evaluation of Analytical Data.
Appendix 2. Some Standard and Formal Electrode Potentials.
Appendix 3. Compounds for Preparing Standard Solutions of Some Common Elements.
Appendix 4. Common Acronyms Encountered in Chemical Instrumentation.
Answers to Selected Problems.
Index.

PRINCIPLES OF INSTRUMENTAL ANALYSIS has long been the standard for courses that deal with the principles and applications of modern analytical instruments. Now with their new Sixth Edition, authors Douglas A. Skoog, F. James Holler, and Stanley R. Crouch infuse their popular text with updated techniques as well as new Instrumental Analysis in Action case studies. The book’s updated material enhances its proven approach, which places an emphasis on the theoretical basis of each type of instrument, its optimal area of application, its sensitivity, its precision, and its limitations. PRINCIPLES OF INSTRUMENTAL ANALYSIS also introduces students to elementary analog and digital electronics, computers, and treatment of analytical data.
A book companion website is available, providing students with tutorials on instrumental methods, Excel files of data analysis and simulations of analytical techniques to help them visualize important concepts in this course, and selected papers from the chemical literature to stimulate interest and provide background information for study.