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Prologue
Preface

INTRODUCTION
Chapter 1 Welcome to Molecular Biology

PART I The Structure of Proteins, Nucleic Acids, and Macromolecular Complexes
Chapter 2 Macromolecules
Chapter 3 Nucleic Acids
Chapter 4 The Physical Structure of Protein Molecules
Chapter 5 Macromolecular Interactions and the Structure of Complex Aggregates

PART II Function of Macromolecules
Chapter 6 The Genetic Material
Chapter 7 DNA Replication
Chapter 8 Transcription
Chapter 9 Translation
Chapter 10 Mutations, Mutagenesis, and DNA Repair

PART III Coordination of Macromolecular Function in Cells
Chapter 11 Regulation of Gene Activity in Prokaryotes
Chapter 12 Regulation of Gene Activity in Eukaryotes
Chapter 13 Genomics and Proteomics Drive Information-Age Biology

PART IV Experimental Manipulation of Macromolecules
Chapter 14 Transposons, Plasmids, and Bacteriophage
Chapter 15 Recombinant DNA and Genetic Engineering: Molecular Tailoring of Genes
Chapter 16 Molecular Biology is Expanding Its Reach

Appendices
Postscript to Your Review of Molecular Biology
Chemical Principles Important for Understanding Molecular Biology
List of Essential Concepts of Molecular Biology

Glossary
Answers to Questions and Problems
Index

Essentials of Molecular Biology, Fourth Edition focuses on the fundamental aspects of molecular structure and function by reviewing key features and along the way, capsulizing them as a series of concise concepts. Thus, students are encouraged to place the reductionist knowledge of molecular biology into broad contexts and thereby develop both academic and personal meaning for this discipline.

＊＊Key Features＊＊
- A layering approach to knowledge construction is employed, developing complexity chapter-by-chapter, rather than presenting a series of detail-laden descriptions all at once.

- The revision of Essentials of Molecular Biology has avoided expansion, and thereby continued to emphasize its most important virtue -- it captures the essence of each major aspect of the discipline of molecular biology, from review of structure to discussion of proteomics!

- Genomics, bioinformatics, and proteomics chapter -- Cutting-edge research strategies are reviewed, for the first time in a molecular biology textbook!

- A Postscript has been added that reviews the most surprising developments in molecular biology over the past two decades and dares to look ahead to potential discoveries. The Prologue also provides tips for students who want to continue their study of molecular biology.

- The content and format were extensively field tested by hundreds of undergraduate students at Indiana University throughout the revision process.